Yoshihiro Urade Selected Research

Ischemia

1/2014	Endogenous prostaglandin D2 and its metabolites protect the heart against ischemia-reperfusion injury by activating Nrf2.
6/2009	Glucocorticoid protects rodent hearts from ischemia/reperfusion injury by activating lipocalin-type prostaglandin D synthase-derived PGD2 biosynthesis.
4/2007	Prostaglandin D2 protects neonatal mouse brain from hypoxic ischemic injury.

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Yoshihiro Urade Research Topics

Disease

23	Inflammation (Inflammations) 01/2021 - 03/2004
11	Sleep Initiation and Maintenance Disorders (Insomnia) 01/2021 - 11/2006
9	Neoplasms (Cancer) 01/2022 - 02/2007
6	Hypoxia (Hypoxemia) 01/2021 - 04/2007
6	Pain (Aches) 01/2021 - 08/2002
6	Narcolepsy 01/2021 - 08/2008
6	Insulin Resistance 01/2019 - 04/2011
6	Body Weight (Weight, Body) 01/2019 - 01/2004
6	Hypersensitivity (Allergy) 07/2011 - 01/2002
5	Infections 01/2021 - 07/2011
5	Pneumonia (Pneumonitis) 01/2016 - 01/2002
5	Globoid Cell Leukodystrophy (Krabbe Disease) 06/2007 - 06/2002
4	Obesity 01/2019 - 04/2011
4	Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker) 08/2013 - 10/2002
4	Atherosclerosis 01/2009 - 08/2005
3	Normal Pressure Hydrocephalus 01/2024 - 12/2003
3	Asthma (Bronchial Asthma) 09/2021 - 01/2002
3	Fibrosis (Cirrhosis) 11/2020 - 04/2011
3	Seizures (Absence Seizure) 11/2018 - 03/2014
3	Alzheimer Disease (Alzheimer's Disease) 04/2014 - 04/2007
3	Ischemia 01/2014 - 04/2007
3	Diabetic Nephropathies (Diabetic Nephropathy) 11/2012 - 09/2002
3	Necrosis 11/2011 - 10/2002
3	Pathologic Processes 02/2009 - 12/2002
3	Atherosclerotic Plaque (Atheroma) 01/2009 - 08/2007
3	Demyelinating Diseases (Demyelinating Disease) 04/2006 - 06/2002
2	Hyperplasia 09/2021 - 07/2015
2	Nasal Polyps (Nasal Polyp) 09/2021 - 07/2007
2	Rhinosinusitis 09/2021 - 01/2009
2	Acute Retinal Necrosis Syndrome 01/2021 - 01/2020
2	Cataplexy 01/2021 - 01/2018
2	Carcinogenesis 11/2020 - 06/2014
2	Disorders of Excessive Somnolence (Hypersomnia) 01/2018 - 09/2017
2	Nervous System Diseases (Neurological Disorders) 01/2018 - 06/2007
2	Melanoma (Melanoma, Malignant) 01/2018 - 01/2006
2	Squamous Cell Carcinoma of Head and Neck 01/2018 - 06/2006
2	African Trypanosomiasis (Nagana) 09/2017 - 12/2002
2	Hyperalgesia 10/2014 - 02/2011
2	Neuralgia (Stump Neuralgia) 10/2014 - 02/2011
2	Adenoma (Adenomas) 08/2014 - 02/2007
2	Colonic Neoplasms (Colon Cancer) 06/2014 - 02/2007
2	Colitis 06/2014 - 03/2011
2	Reperfusion Injury 01/2014 - 06/2009
2	Cardiovascular Diseases (Cardiovascular Disease) 12/2013 - 06/2007
2	Wasting Syndrome (Wasting Disease) 08/2013 - 05/2009
2	Glucose Intolerance 02/2013 - 08/2005
2	Multiple Sclerosis 01/2013 - 06/2007
2	Mental Disorders (Mental Disorder) 10/2012 - 08/2005
2	Contact Dermatitis (Eczema, Contact) 07/2011 - 08/2006
2	Infarction (Infarctions) 06/2009 - 04/2007

Drug/Important Bio-Agent (IBA)

49	prostaglandin R2 D-isomerase (prostaglandin D2 synthase)IBA 01/2024 - 01/2002
42	Prostaglandin D2IBA 01/2023 - 04/2003
35	LipocalinsIBA 01/2024 - 01/2002
33	ProstaglandinsIBA 01/2021 - 06/2002
16	Prostaglandins DIBA 01/2014 - 01/2002
13	Proteins (Proteins, Gene)FDA Link 01/2021 - 06/2002
8	Messenger RNA (mRNA)IBA 11/2020 - 04/2005
8	EnzymesIBA 11/2018 - 06/2006
6	prostaglandin D2 receptorIBA 01/2023 - 08/2006
6	Dinoprostone (PGE2)FDA Link 07/2015 - 06/2006
6	Glucose (Dextrose)FDA LinkGeneric 02/2013 - 08/2005
5	Biomarkers (Surrogate Marker)IBA 01/2024 - 12/2008
5	CytokinesIBA 01/2020 - 01/2002
5	LipidsIBA 01/2017 - 01/2002
5	Prostaglandin H2 (PGH(2))IBA 06/2011 - 12/2002
4	OrexinsIBA 01/2021 - 11/2009
4	Hypnotics and Sedatives (Sedatives)IBA 01/2021 - 04/2014
4	Prostaglandins EIBA 02/2011 - 06/2006
3	RNA (Ribonucleic Acid)IBA 01/2021 - 11/2020
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 08/2020 - 09/2009
3	Caffeine (No Doz)FDA LinkGeneric 01/2019 - 08/2009
3	Pentylenetetrazole (Metrazol)IBA 11/2018 - 03/2014
3	AntigensIBA 07/2015 - 06/2006
3	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 01/2014 - 06/2006
3	Prostaglandins FIBA 03/2009 - 12/2002
2	Interleukin-4 (Interleukin 4)IBA 01/2022 - 11/2012
2	SteroidsIBA 09/2021 - 10/2012
2	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 09/2021 - 02/2007
2	AntioxidantsIBA 01/2021 - 04/2011
2	Long Noncoding RNAIBA 01/2021 - 11/2020
2	Formyl Peptide Receptors (Formyl Peptide Receptor)IBA 01/2021 - 08/2006
2	Dexamethasone (Maxidex)FDA LinkGeneric 01/2021 - 06/2009
2	CholesterolIBA 01/2019 - 02/2013
2	AdiponectinIBA 01/2019 - 12/2012
2	Amyloid beta-PeptidesIBA 04/2014 - 04/2007
2	AcidsIBA 01/2014 - 03/2013
2	GlucocorticoidsIBA 01/2014 - 06/2009
2	11,15- dioxo- 9- hydroxy- 2,3,4,5- tetranorprostan- 1,20- dioic acidIBA 08/2013 - 12/2011
2	DystrophinIBA 08/2013 - 05/2009
2	Interleukin-13IBA 03/2013 - 11/2012
2	Insulin (Novolin)FDA Link 12/2012 - 04/2011
2	Small Interfering RNA (siRNA)IBA 06/2012 - 07/2011
2	Prostaglandin-E SynthasesIBA 02/2011 - 06/2006
2	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 01/2011 - 06/2006
2	Dopamine (Intropin)FDA LinkGeneric 03/2010 - 11/2009

Therapy/Procedure

8	Therapeutics 09/2021 - 04/2005
2	Lasers (Laser) 01/2023 - 11/2020
2	Kampo Medicine (Kampo) 01/2021 - 06/2014
2	Oral Administration 11/2012 - 11/2011
2	Spinal Injections 10/2012 - 02/2011